Grant Support

The MSU Genomics Core provides many types of sequencing services to both MSU researchers and the wider research community.  Equipment within the Core includes one Element Biosciences AVITI24 and one Element Biosciences AVITI for next-generation short-read sequencing of Illumina-style libraries.  A 10x Genomics Chromium X is used to generate single cell sequencing libraries.  A 10x Genomics CytAssist is used to prepare Visium spatial transcriptome libraries.  Three Oxford Nanopore PromethION P2 solo instruments are used for long-read DNA, cDNA and direct RNA sequencing.  Size-specific shearing of nucleic acids is achieved with a Covaris M220 Sonicator.  Sequencing library size-selection is performed with a Sage Science Pippin Prep.  Two Agilent 4200 TapeStations are used for RNA and DNA quality and size analysis.  Fluorescence-based nucleic acid quantification is performed on Invitrogen Qubit and Qubit Flex devices.