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Pricing

Pricing is identical for MSU researchers and for off-campus researchers.  However, payments from non-MSU accounts (i.e. off-campus researchers) will be subject to a 2% University Administrative Fee.  MSU also requires the addition of a 26% Facilities and Administrative Cost charge to services provided to for-profit companies.

 

TapeStation Analysis

TapeStation Sample Requirements and Service Description
TapeStation Submission Form

DESCRIPTION PRICE
HS RNA assay (≤ 6 samples), each $14 (minimum fee $36)
HS RNA assay (7 - 47 samples), each $10
HS RNA assay (≥ 48 samples), each $7
D1000 HS assay (≤ 6 samples), each $13 (minimum fee $28)
D1000 HS assay (7 - 47 samples), each $10
D1000 HS assay (≥ 48 samples), each $8
D5000 HS assay (≤ 6 samples), each $17 (minimum fee $28)
D5000 HS assay (7 - 47 samples), each $10
D5000 HS assay (≥ 48 samples), each $8
Genomic DNA assay (≤ 6 samples), each $18 (minimum fee $29)
Genomic DNA assay (7 - 47 samples), each $11
Genomic DNA assay (≥ 48 samples), each $9

 

Qubit Flex High Throughput Quantification

Minimum of 72 samples required for this service.

Qubit Flex Quantification Sample Requirements
Qubit Flex Quantification Submission Form

DESCRIPTION PRICE
Qubit Flex, first 72 samples $203
Qubit Flex, each additional column (8 samples/column) $23

 

Qubit Self-Service Quantification

Visit the Common Use Equipment webpage for instructions to reserve the qubit.

For accurate quantification, the two kit standards must be measured with each batch of samples that are processed.  The standards are charged at the same rate as a sample, therefore, if you are quantifying two samples the cost will be $9 (4 x $2.25) because of the two required standards.

DESCRIPTION PRICE
Qubit dsDNA BR assay, each $2.25
Qubit dsDNA HS assay, each $2.25
Qubit RNA BR assay, each $2.25
Qubit RNA HS assay, each $2.25

 

Illumina-Compatible Library Preparation

DNA Library Preparation Descriptions and Sample Requirements
RNA-Seq Library Preparation Descriptions and Sample Requirements
DNA/RNA Submission Forms

DESCRIPTION PRICE
Shotgun DNA Library (≤ 12 samples), each $93
Shotgun DNA Library (13 - 47 samples), each $81
Shotgun DNA Library (≥ 48 samples), each $74
Methyl-Seq DNA Library (8 - 19 samples), each $223
Methyl-Seq DNA Library (≥ 20 samples), each $166
RNA-Seq (poly-A selection) Library (≤ 12 samples), each $98
RNA-Seq (poly-A selection) Library (13 - 47 samples), each $87
RNA-Seq (poly-A selection) Library (≥ 48 samples), each $80
RNA-Seq (rRNA depletion) Library (≤ 12 samples), each
(researcher provides rRNA depletion kit)
$113
RNA-Seq (rRNA depletion) Library (13 - 47 samples), each
(researcher provides rRNA depletion kit)
$94
RNA-Seq (rRNA depletion) Library (≥ 48 samples), each
(researcher provides rRNA depletion kit)
$84
QuantSeq 3' mRNA-Seq Library (≥ 72 samples), each $66
Small RNA or miRNA Library (≥ 12 samples), each $247

 

Amplicon Library Preparation

Amplicon Library Preparation Descriptions and Sample Requirements
Amplicon Submission Form

DESCRIPTION PRICE
16S V4 Amplicon library (24 - 380 samples) $5.50 per sample plus $302 per plate
Amplicon barcoding (24 - 570 samples) $5.50 per sample plus $302 per plate
QC of amplicon library pool (prepared by Genomics Core) $68

 

 

Library/Pool Quality Control

DESCRIPTION PRICE
QC of user-prepared library or pool $68
qPCR of Genomics Core prepared library pool
(excluding amplicon library pools)
$28

 

NovaSeq 6000

The options in the table below are available for purchase by the lane.  Download the PDF of sequencing available by the lane (includes cost per Gbp).

Other sequencing options are available by the flow cell.  Download the PDF for flow cell pricing.

DESCRIPTION PRICE
SP 1x100 bp single end lane (362 M reads, 36 Gbp) $1,729
SP 2x150 bp paired end lane (362 M read pairs, 108 Gbp) $2,463
S1 1x100 bp single end lane (725 M reads, 73 Gbp) $2,910
S1 2x150 bp paired end lane (725 M read pairs, 218 Gbp) $4,204
S4 2x150 bp paired end lane (2,250 M read pairs, 675 Gbp) $5,953
S4-shared (1/10th lane) 2x150 bp paired end
(200 M read pairs, 60 Gbp)
$694

 

MiSeq

Download the PDF for detailed run specifications.

DESCRIPTION PRICE
v2 Standard 2x150 bp paired end run $1,536
v2 Standard 2x250 bp paired end run $1,672
v2 Micro 2x150 bp paired end run $770
v2 Nano 2x150 bp paired end run $582
v2 Nano 2x250 bp paired end run $720
v3 2x75 bp paired end or 1x150 bp single end run $1,313
v3 2x300 bp paired end run $2,245

 

Oxford Nanopore Library Preparation

See our Oxford Nanopore Technology page and our Nanopore Sample Requirements page for more information.

Oxford Nanopore Submission Form

DESCRIPTION PRICE
Ligation Sequencing Kit (LSK114), each $787
Ligation Sequencing with Native Barcoding Kit (NBD114.24) $690 + $144/barcode
(up to 24 samples)
Rapid Barcoding Kit (RBK114.24) $472 (up to 24 samples)
Direct RNA Sequencing Kit (RNA004), each $559
cDNA-PCR Sequencing Kit (PCS109/PSC111), each $616
cDNA-PCR Sequencing Kit with Barcoding (PCB109/PCB111.24) $445 + $114/barcode
(up to 24 samples)

Oxford Nanopore Flow Cells

DESCRIPTION PRICE
GridION R10.4.1 $899
PromethION R10.4.1 $1,095

 

10X Genomics Chromium Single Cell Library Preparation

A consultation with the Genomics Core is required prior to beginning experiment.  Contact us at gtsf@msu.edu to schedule consult.  Researcher is required to purchase 10X kit(s).

DESCRIPTION PRICE
Chromium Next GEM Single Cell 3′ Kit v3.1
(1 sample)
$570
Chromium Next GEM Single Cell 3′ Kit v3.1
(2 - 4 samples), each
$337
Chromium Next GEM Single Cell 3′ Kit v3.1
(5 - 8 samples), each
$223
Chromium Next GEM Single Cell ATAC Kit v2
(1 sample)
$508
Chromium Next GEM Single Cell ATAC Kit v2
(2 - 4 samples), each
$285
Chromium Next GEM Single Cell ATAC Kit v2
(5 - 8 samples), each
$177
Chromium Next GEM Single Cell Multiome
ATAC + Gene Expression (1 sample)
$1,036
Chromium Next GEM Single Cell Multiome
ATAC + Gene Expression (2 - 4 samples), each
$641
Chromium Next GEM Single Cell Multiome
ATAC + Gene Expression (5 - 8 samples), each
$378

 

Sanger Sequencing

Sanger Sequencing Sample Requirements
The Sanger Sequencing Submission Form and Custom Naming Template can be downloaded from our Forms webpage.

DESCRIPTION PRICE
Standard reaction (≤ 8 samples in individual tubes), each $7
Standard reaction (9 - 16 samples in 8-strip PCR tubes or
96-well plate), each
$6
Standard reaction (≥ 17 samples in 96-well PCR plate), each $3.50
*NEW* High Throughput Standard Reaction, researcher
adds primer (≥ 48 samples in 96-well PCR plate), each
$2.75
1st Tier reaction (≤ 8 samples in individual tubes), each $8
1st Tier reaction (9 - 16 samples in 8-strip PCR tubes or
96-well plate), each
$7
1st Tier reaction (≥ 17 samples in 96-well PCR plate), each $4.50

 

Genotyping/GeneScan/Fragment Analysis

GeneScan/Fragment Analysis submission form

DESCRIPTION PRICE
GeneScan 500 ROX dye Size Standard, each $2.25 (minimum fee $50)
GeneScan 500 LIZ dye Size Standard, each $2.25 (minimum fee $50)
GeneScan 400HD ROX dye Size Standard, each $2.25 (minimum fee $50)
MapMarker X-Rhodamine Labeled 50-1000bp, each $1.80 (minimum fee $50)
GeneScan 1200 LIZ dye Size Standard, each $2.40 (minimum fee $50)

 

QuantStudio 7 Flex qPCR

Researcher submits fully assembled reactions in 96-well or 384-well plate(s).
The qPCR submission form can be downloaded from our Forms webpage.
Please see our qPCR webpage for more information.

DESCRIPTION PRICE
1 x 96-well plate $59
2 x 96-well plates $69
3 x 96-well plates $80
4 x 96-well plates $90
1 x 384-well plate $38
Dissociation Curve $8.50
384-well optical plate, each $5
Optical sealing film, each $3

 

NanoString nCounter

Price does not include reagents from NanoString. The listed prices are for sample processing only.

See our NanoString Sample Requirements page for more information.  

NanoString submission form

DESCRIPTION PRICE
mRNA assay with Gene Expression Panel,
Custom CodeSet or Elements TagSet
$247/12 sample cassette
miRNA assay with NanoString miRNA Panel $251/12 sample cassette
Multiplexed mRNA assay with nCounter PlexSet $356/96 samples in 12 well cassette

 

Covaris Sonicator (Self-Service)

Visit the Common Use Equipment webpage for instructions to reserve the Covaris.

DESCRIPTION PRICE
Sample Shearing $2
Small Tube (130 µl tube, p/n 520045), each $6.50*
Large Tube (1 ml tube, p/n 520135), each $7

*6/8/2023 - Due to increased costs from the supplier, the cost has been increased to $6.50.

 

Size Selection

DESCRIPTION PRICE

Select-a-Size (Zymo part number D4080)

$18 per library

Blue Pippin Size Selection of 1 to 4 libraries at one time
(100 - 600 bp size range)

Libraries must be similar size.

$124